Colon Targeted Drug Delivery System – A Review.
نویسندگان
چکیده
منابع مشابه
Colon Targeted Drug Delivery System: a Review
Day by day there are new developments in field of colon specific drug delivery system. Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon like Crohn’s disease, ulcerative colitis, etc. but also for the systemic delivery of proteins, therapeutic peptides, anti-asthmatic drugs, antihypertensive...
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In the current year colonic drug delivery has gained significance for delivery of drug for the treatment of local diseases related with colon and systemic delivery of therapeutic peptides and proteins. Management could be more effective if it is possible for drug to be directly delivered to colon. This article gives an overview on different approaches utilized for colon specific drug delivery.
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The main objective of the present study was to develop colon targeted drug delivery systems for Nitrofurantoin using guar gum as a carrier. Matrix tablets containing various proportions of guar gum were prepared by wet granulation technique using starch paste as a binder. The in-vitro drug release study was undertaken at 37±0.5°C in 0.1N Hcl for 2 hr; followed by pH 7.4 phosphate buffer (3hr) f...
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ژورنال
عنوان ژورنال: Journal of Current Pharma Research
سال: 2018
ISSN: 2230-7834,2230-7842
DOI: 10.33786/jcpr.2018.v09i01.007